Junichiro Hiro Selected Research

2- (2- methoxy- 4- nitrophenyl)- 3- (4- nitrophenyl)- 5- (2,4- disulfophenyl)- 2H tetrazolium monosodium salt

6/2008	Mechanism of resistance to chemoradiation in p53 mutant human colon cancer.
8/2007	Does preoperative chemo-radiotherapy enhance the expression of vascular endothelial growth factor in patients with rectal cancer?
12/2006	Schedule-dependent cytotoxicity of 5-fluorouracil and irinotecan in a colon cancer cell line.
11/2006	The optimal schedule for 5-fluorouracil radiosensitization in colon cancer cell lines.
2/2006	in vitro synergistic antitumor activity of a combination of 5-fluorouracil and irinotecan in human colon cancer.

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Junichiro Hiro Research Topics

Disease

26	Colorectal Neoplasms (Colorectal Cancer) 10/2022 - 12/2004
21	Rectal Neoplasms (Rectal Cancer) 04/2024 - 11/2006
20	Neoplasms (Cancer) 04/2022 - 12/2004
15	Colonic Neoplasms (Colon Cancer) 08/2017 - 02/2006
12	Neoplasm Metastasis (Metastasis) 12/2020 - 12/2005
9	Lymphatic Metastasis 01/2021 - 03/2015
7	Ulcerative Colitis 01/2019 - 02/2014
6	Stomach Neoplasms (Stomach Cancer) 10/2020 - 12/2018
5	Inflammation (Inflammations) 02/2021 - 12/2014
3	Esophageal Neoplasms (Esophageal Cancer) 01/2021 - 11/2017
3	Surgical Wound Infection 03/2020 - 01/2017
3	Sarcopenia 01/2019 - 01/2017
2	Pathologic Constriction (Stenosis) 01/2021 - 12/2019
2	Anastomotic Leak 01/2020 - 01/2018
2	Fistula 05/2017 - 09/2013
2	Carcinogenesis 01/2016 - 12/2014
2	Residual Neoplasm 04/2012 - 03/2008
1	Sepsis (Septicemia) 09/2023
1	Infections 09/2023
1	Peripheral Nervous System Diseases (PNS Diseases) 08/2022
1	Morbid Obesity 04/2022
1	Weight Loss (Weight Reduction) 04/2022
1	Fibrosis (Cirrhosis) 01/2021
1	Paralysis (Palsy) 01/2021
1	Diarrhea 04/2019
1	Emergence Delirium 02/2019
1	Chronic Obstructive Pulmonary Disease (COPD) 02/2019
1	Carcinoma (Carcinomatosis) 01/2019
1	Disease Progression 04/2018
1	Hypoalbuminemia 01/2018
1	Crohn Disease (Crohn's Disease) 01/2017
1	Adenomatous Polyps 01/2016
1	Adenoma (Adenomas) 01/2016
1	Acute-Phase Reaction 10/2015
1	Colic (Abdominal Cramps) 02/2015
1	Vaginal Fistula 11/2014
1	Mucinous Adenocarcinoma (Mucinous Carcinoma) 09/2013

Drug/Important Bio-Agent (IBA)

12	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2014
9	Fluorouracil (Carac)FDA LinkGeneric 05/2013 - 02/2006
6	Proteins (Proteins, Gene)FDA Link 04/2021 - 10/2010
5	Indicators and Reagents (Reagents)IBA 01/2021 - 08/2017
5	C-Reactive ProteinIBA 01/2021 - 01/2017
5	Irinotecan (Camptosar)FDA LinkGeneric 04/2019 - 12/2004
5	2- (2- methoxy- 4- nitrophenyl)- 3- (4- nitrophenyl)- 5- (2,4- disulfophenyl)- 2H tetrazolium monosodium saltIBA 06/2008 - 02/2006
4	MicroRNAs (MicroRNA)IBA 01/2019 - 01/2016
4	AlbuminsIBA 01/2018 - 01/2017
4	Messenger RNA (mRNA)IBA 12/2017 - 11/2006
3	Serum AlbuminIBA 01/2019 - 01/2018
3	GlobulinsIBA 01/2018 - 01/2017
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 08/2022 - 04/2019
2	HSP47 Heat-Shock Proteins (Heat Shock Protein 47)IBA 12/2020 - 01/2017
2	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 01/2019 - 03/2015
2	imidazoleacetic acid (IMAC)IBA 01/2019 - 04/2018
2	RNA (Ribonucleic Acid)IBA 12/2018 - 09/2012
2	Leucovorin (Folinic Acid)FDA Link 05/2013 - 01/2010
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2012 - 08/2007
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 04/2012 - 10/2006
2	Paclitaxel (Taxol)FDA LinkGeneric 10/2010 - 05/2007
1	16S Ribosomal RNAIBA 10/2022
1	Menthol FDA Link 08/2022
1	CTLA-4 AntigenIBA 12/2020
1	Tumor Biomarkers (Tumor Markers)IBA 01/2020
1	LigandsIBA 03/2019
1	EnzymesIBA 12/2018
1	Fish OilsIBA 01/2018
1	ezrinIBA 12/2017
1	AntibodiesIBA 01/2017
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017
1	Monocyte Chemoattractant ProteinsIBA 09/2016
1	CytokinesIBA 09/2016
1	Calcibiotic Root Canal SealerIBA 01/2016
1	Circulating MicroRNAIBA 01/2016
1	Prednisolone (Predate)FDA LinkGeneric 09/2015
1	Angiopoietin-Like Protein 2IBA 12/2014
1	Small Interfering RNA (siRNA)IBA 12/2014
1	Bevacizumab (Avastin)FDA Link 05/2013
1	Opioid Analgesics (Opioids)IBA 01/2013
1	Phosphotransferases (Kinase)IBA 01/2013
1	protein phosphatase 4IBA 01/2013
1	Cell Adhesion MoleculesIBA 11/2012

Therapy/Procedure

12	Chemoradiotherapy 01/2021 - 04/2012
11	Therapeutics 01/2019 - 12/2004
10	Drug Therapy (Chemotherapy) 08/2022 - 12/2004
7	Restorative Proctocolectomy 01/2019 - 02/2014
6	Neoadjuvant Therapy 04/2021 - 11/2006
4	Colectomy 04/2022 - 02/2015
4	Gastrectomy 10/2020 - 06/2019
4	Colonic Pouches (S Pouch) 05/2017 - 01/2011
3	Radiotherapy 05/2013 - 12/2005
2	Surgical Instruments (Clip) 02/2021 - 02/2015
2	Esophagectomy 01/2021 - 02/2019
2	Proctectomy 01/2019 - 05/2017
1	Robotic Surgical Procedures 04/2024
1	Catheters 09/2023
1	Hemorrhoidectomy 01/2021
1	Immunotherapy 12/2020
1	Operative Surgical Procedures 12/2019
1	Ileostomy 01/2017
1	Lymph Node Excision (Lymph Node Dissection) 02/2015
1	Laparotomy 03/2014